Overview

  • Product name

    ZLN005, PGC-1alpha transcriptional activator
  • Description

    PGC-1α transcriptional activator. Activates AMPK.
  • Biological description

    PGC-1α transcriptional activator. Activates AMPK. Stimulates PGC-1α expression. Increases fat oxidation. Improves glucose and pyruvate tolerance. Increases insulin sensitivity. Shows antidiabetic effects in vivo.
  • Purity

    > 95%
  • CAS Number

    49671-76-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(4-tert-Butylphenyl)-1H-benzimidazole
  • Molecular weight

    250.34
  • Molecular formula

    C17H18N2
  • PubChem identifier

    899323
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 10 mM and in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Zhang LN  et al. Novel small-molecule PGC-1a transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes 62:1297-307 (2013). Read more (PubMed: 23250358) »

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