Anti-ZMYM2/RAMP antibody (ab106624)
Key features and details
- Rabbit polyclonal to ZMYM2/RAMP
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-ZMYM2/RAMP antibody -
Description
Rabbit polyclonal to ZMYM2/RAMP -
Host species
Rabbit -
Specificity
At least three isoforms of ZMYM2/RAMP are known to exist; ab106624 will detect only the longest isoform. It is predicted to not cross react with other ZMYM protein family members.
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Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- EL4 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106624 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.125 - 0.25 µg/ml. Predicted molecular weight: 155 kDa.
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Notes |
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WB
Use a concentration of 0.125 - 0.25 µg/ml. Predicted molecular weight: 155 kDa. |
Target
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Function
May function as a transcription factor. -
Involvement in disease
Note=A chromosomal aberration involving ZMYM2 may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Translocation t(8;13)(p11;q12) with FGFR1. SCLL usually presents as lymphoblastic lymphoma in association with a myeloproliferative disorder, often accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow. -
Sequence similarities
Contains 9 MYM-type zinc fingers. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 76007 Mouse
- SwissProt: Q9CU65 Mouse
- Unigene: 31417 Mouse
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Form
There are 2 isoforms produced by alternative splicing. -
Alternative names
- FIM antibody
- Fused in myeloproliferative disorders protein antibody
- MYM antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab106624 has been referenced in 3 publications.
- Meijer BJ et al. Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2. Sci Rep 11:9892 (2021). PubMed: 33972635
- Cibis H et al. Characterization of the zinc finger proteins ZMYM2 and ZMYM4 as novel B-MYB binding proteins. Sci Rep 10:8390 (2020). PubMed: 32439918
- Connaughton DM et al. Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations. Am J Hum Genet 107:727-742 (2020). PubMed: 32891193