Anti-ZNF217 antibody (ab117798)
Key features and details
- Rabbit polyclonal to ZNF217
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ZNF217 antibody
See all ZNF217 primary antibodies -
Description
Rabbit polyclonal to ZNF217 -
Host species
Rabbit -
Tested applications
Suitable for: IPmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
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Immunogen
Synthetic peptide, corresponding to a region between amino acids 100-150 of Human ZNF217 (NP_006517.1).
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Positive control
- Jurkat whole cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris buffered saline
pH 7-8 -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab117798 was affinity purified using an epitope specific to ZNF217 immobilized on solid support. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab117798 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IP |
Use at 2-10 µg/mg of lysate.
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| Notes |
|---|
|
IP
Use at 2-10 µg/mg of lysate. |
Target
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Function
Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'. -
Sequence similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 7 C2H2-type zinc fingers. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 7764 Human
- Omim: 602967 Human
- SwissProt: O75362 Human
- Unigene: 155040 Human
- Unigene: 711564 Human
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Alternative names
- ZABC 1 antibody
- ZABC1 antibody
- Zinc finger protein 217 antibody
see all
Images
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Immunoprecipitation - Anti-ZNF217 antibody (ab117798)Lane 1: Staining of ZNF217 in Jurkat whole cell lysate immunoprecipitated using ab117798 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: control IgG. Predicted band size : 115 kDa. Exposure time: 30 seconds
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab117798 has been referenced in 2 publications.
- Pang B et al. Landscape of tumor suppressor long noncoding RNAs in breast cancer. J Exp Clin Cancer Res 38:79 (2019). PubMed: 30764831
- Zhu HY et al. Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-ß2 by targeting ZNF217 via miR-200c in keloid fibroblasts. Sci Rep 6:24728 (2016). ChIP . PubMed: 27090737