Anti-ZNF217 antibody (ab117798)

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Overview

  • Product name

    Anti-ZNF217 antibody
    See all ZNF217 primary antibodies

  • Description

    Rabbit polyclonal to ZNF217

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IPmore details
    Unsuitable for: WB

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan

  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 100-150 of Human ZNF217 (NP_006517.1).

  • Positive control

    • Jurkat whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab117798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.

    • Target

    • Function

      Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.

    • Sequence similarities

      Belongs to the krueppel C2H2-type zinc-finger protein family.
      Contains 7 C2H2-type zinc fingers.

    • Cellular localization

      Nucleus.
    • Information by UniProt

    • Database links

      • Alternative names

        • ZABC 1 antibody
        • ZABC1 antibody
        • Zinc finger protein 217 antibody
        • ZN 217 antibody
        • ZN217 antibody
        • ZN217_HUMAN antibody
        • ZNF 217 antibody
        • ZNF217 antibody
        see all

      Images

      • Immunoprecipitation - Anti-ZNF217 antibody (ab117798)
        Immunoprecipitation - Anti-ZNF217 antibody (ab117798)
        Lane 1: Staining of ZNF217 in Jurkat whole cell lysate immunoprecipitated using ab117798 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: control IgG. Predicted band size : 115 kDa. Exposure time: 30 seconds

      References

      This product has been referenced in:

      • Pang B  et al. Landscape of tumor suppressor long noncoding RNAs in breast cancer. J Exp Clin Cancer Res 38:79 (2019). Read more (PubMed: 30764831) »
      • Zhu HY  et al. Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-ß2 by targeting ZNF217 via miR-200c in keloid fibroblasts. Sci Rep 6:24728 (2016). ChIP . Read more (PubMed: 27090737) »
      See all 2 Publications for this product

      Publishing research using ab117798? Please let us know so that we can cite the reference in this datasheet.

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