Overview

  • Product name

    Anti-ZNF238 antibody
  • Description

    Rabbit polyclonal to ZNF238
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 228-498 of Human ZNF238 (BC036677).

  • Positive control

    • K562 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118471 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).

Target

  • Function

    Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
  • Tissue specificity

    Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.
  • Sequence similarities

    Contains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Nucleus. Associates with condensed chromatin.
  • Information by UniProt
  • Database links

  • Alternative names

    • C2H2171 antibody
    • 58 kDa repressor protein antibody
    • C2H2 171 antibody
    • RP58 antibody
    • TAZ 1 antibody
    • TAZ-1 antibody
    • TAZ1 antibody
    • Transcriptional repressor RP58 antibody
    • Translin associated zinc finger protein 1 antibody
    • Translin-associated zinc finger protein 1 antibody
    • ZBTB18 antibody
    • Zinc finger and BTB domain containing protein 18 antibody
    • Zinc finger and BTB domain-containing protein 18 antibody
    • Zinc finger protein 238 antibody
    • Zinc finger protein C2H2 171 antibody
    • Zinc finger protein C2H2-171 antibody
    • ZN238_HUMAN antibody
    • ZNF238 antibody
    see all

Images

  • Anti-ZNF238 antibody (ab118471) at 1/500 dilution + K562 cell lysate

    Predicted band size: 58 kDa

References

This product has been referenced in:

See 1 Publication for this product

Customer reviews and Q&As

Question
Answer

DISCOUNT CODE: ***
Expiration date: April 5, 2013
Value: $337

This code will give you $337 off your next order before the expiration date. To redeem this offer, please submit an Abreview for ab118471 in ChIP and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active.
For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews.

code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

The terms and conditions applicable to this offer can be found here: www.abcam.com/abtrial.

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