Overview

  • Product name

    Anti-ZNF312/FEZF2 antibody
    See all ZNF312/FEZF2 primary antibodies
  • Description

    Rabbit polyclonal to ZNF312/FEZF2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human ZNF312/FEZF2 aa 1-50 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    MASSASLETM VPPACPRAGA SPATSKTLAF SIERIMAKTS EPRAPFEPRP


    Database link: Q8TBJ5

  • Positive control

    • IHC-P: Rat brain tissue.
  • General notes

     This product was previously labelled as ZNF312

     

Properties

Applications

Our Abpromise guarantee covers the use of ab214186 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    ZNF312, also known as Fezf2 or Fez-like, is a zinc finger protein that acts as a transcriptional repressor during the development of corticospinal motor neurons and other subcerebral projection neurons. ZNF312 is expressed by early progenitor cells in the ventricular zone. It regulates the fate choice of subcortical projection neurons in the developing cerebral cortex. This protein is expressed in the developing cortical plate during early embryonic development. During late embryonic development and early postnatal development, ZNF312 expression disappears from the cortical progenitors and becomes restricted to the subplate nad the prospective layer V and VI pyramidal neurons.
  • Cellular localization

    Nuclear
  • Database links

  • Alternative names

    • Fez antibody
    • FEZ family zinc finger protein 2 antibody
    • FEZF 2 antibody
    • FEZF2 antibody
    • FEZL antibody
    • Forebrain embryonic zinc finger like protein 2 antibody
    • TOF antibody
    • ZFP 312 antibody
    • ZFP312 antibody
    • Zinc finger FEZL antibody
    • Zinc finger protein 312 antibody
    • Zinc finger protein FEZ like antibody
    • ZNF 312 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin-embedded rat brain tissue sections labeling ZNF312/FEZF2 using ab214186 at a 1/200 dilution. DAB staining.

References

This product has been referenced in:

  • Chen Z  et al. Loss of Fezf2 promotes malignant progression of bladder cancer by regulating the NF-?B signaling pathway. Lab Invest 98:1225-1236 (2018). Read more (PubMed: 29925938) »
See 1 Publication for this product

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