Anti-ZNF750 antibody (ab121730)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-ZNF750 antibody
See all ZNF750 primary antibodies -
Description
Rabbit polyclonal to ZNF750 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence, corresponding to amino acids 73-187 of Human ZNF750.
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Positive control
- Human stomach tissue.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab121730 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Perform Heat Induced Epitope Retrieval (HIER) at pH 6 using a pressure boiler as heat source. |
Target
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Tissue specificity
Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts. -
Involvement in disease
Defects in ZNF750 are the cause of Seborrhea-like dermatitis with psoriasiform (SLDP) [MIM:610227]. SLDP is characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders. - Information by UniProt
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Database links
- Entrez Gene: 79755 Human
- Omim: 610226 Human
- SwissProt: Q32MQ0 Human
- Unigene: 653124 Human
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Alternative names
- Protein ZNF750 antibody
- ZFP750 antibody
- Zinc finger protein 750 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF750 antibody (ab121730)ab121730 at 1/125 dilution staining ZNF750in Paraffin-embedded Human Stomach tissue by Immunohistochemistry. Note: strong cytoplasmic positivity in parietal cells.
Protocols
Datasheets and documents
References
ab121730 has not yet been referenced specifically in any publications.
