Zoledronic acid, FPP synthase inhibitor (ab141980)
Key features and details
- Highly potent bisphosphonate. FPP synthase inhibitor.
- CAS Number: 118072-93-8
- Purity: > 98%
Soluble in water (up to 2 mg/ml).
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Zoledronic acid, FPP synthase inhibitor -
Description
Highly potent bisphosphonate. FPP synthase inhibitor. -
Purity
> 98% -
CAS Number
118072-93-8 -
Chemical structure
Properties
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Chemical name
(1-Hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid
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Molecular weight
272.09 -
PubChem identifier
68740 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water (up to 2 mg/ml).
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab141980 has been referenced in 2 publications.
- Lu H et al. B7-H3 confers resistance to V?9Vd2 T cell-mediated cytotoxicity in human colon cancer cells via the STAT3/ULBP2 axis. Cancer Immunol Immunother 70:1213-1226 (2021). PubMed: 33119798
- Lu H et al. B7-H3 inhibits the IFN-?-dependent cytotoxicity of V?9Vd2 T cells against colon cancer cells. Oncoimmunology 9:1748991 (2020). PubMed: 32363121