Key features and details
- Non-selective Na+ / Ca2+ channel blocker
- CAS Number: 68291-97-4
- Soluble in water to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameZonisamide, Non-selective Na+ / Ca2+ channel blocker
DescriptionNon-selective Na+ / Ca2+ channel blocker
Broad spectrum antiepileptic with multiple mechanisms of action. Blocks voltage-sensitive Na+ and T-type Ca2+ channels and stimulates BKCa channels. Modulates GABA, glutamate, cholinergic and monoamine neurotransmission. Exhibits free-radical scavenging properties.
Also available in simple stock solutions (ab146711) - add 1 ml of water to get an exact, ready-to-use concentration.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 10 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120369 has not yet been referenced specifically in any publications.