Anti-ZSWIM2 antibody (ab127023)
Key features and details
- Rabbit polyclonal to ZSWIM2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ZSWIM2 antibody
See all ZSWIM2 primary antibodies -
Description
Rabbit polyclonal to ZSWIM2 -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Recombinant fragment, corresponding to a region within amino acids 350-575 of Human ZSWIM2 (UniProt Q8NEG5).
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Positive control
- U87-MG and MCF7 whole cell lysates; NT2D1 and IMR32 cell lysates
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General notes
Store undiluted.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab127023 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| WB |
Human
|
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 73 kDa.
|
| Notes |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 73 kDa. |
Target
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Function
E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes. -
Sequence similarities
Contains 2 RING-type zinc fingers.
Contains 1 SWIM-type zinc finger.
Contains 1 ZZ-type zinc finger. -
Domain
The SWIM-type zinc finger is reqiered for ubiquitination activity. -
Post-translational
modificationsPolyubiquitinated. Polyubiquitination is followed by degradation via the proteasome. - Information by UniProt
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Database links
- Entrez Gene: 151112 Human
- SwissProt: Q8NEG5 Human
- Unigene: 375054 Human
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Alternative names
- E3 ubiquitin-protein ligase ZSWIM2 antibody
- MEKK1-related protein X antibody
- MEX antibody
see all
Images
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Western blot - Anti-ZSWIM2 antibody (ab127023)All lanes : Anti-ZSWIM2 antibody (ab127023) at 1/1000 dilution
Lane 1 : U87-MG whole cell lysate
Lane 2 : MCF7 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 73 kDa
7.5% SDS-PAGE
References (0)
ab127023 has not yet been referenced specifically in any publications.
