Anti-ZSWIM2 antibody (ab127023)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-ZSWIM2 antibody
See all ZSWIM2 primary antibodies -
Description
Rabbit polyclonal to ZSWIM2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 350-575 of Human ZSWIM2 (UniProt Q8NEG5).
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Positive control
- U87-MG and MCF7 whole cell lysates; NT2D1 and IMR32 cell lysates
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General notes
Store undiluted.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab127023 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 73 kDa. |
Target
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Function
E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes. -
Sequence similarities
Contains 2 RING-type zinc fingers.
Contains 1 SWIM-type zinc finger.
Contains 1 ZZ-type zinc finger. -
Domain
The SWIM-type zinc finger is reqiered for ubiquitination activity. -
Post-translational
modificationsPolyubiquitinated. Polyubiquitination is followed by degradation via the proteasome. - Information by UniProt
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Database links
- Entrez Gene: 151112 Human
- SwissProt: Q8NEG5 Human
- Unigene: 375054 Human
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Alternative names
- E3 ubiquitin-protein ligase ZSWIM2 antibody
- MEKK1-related protein X antibody
- MEX antibody
see all
Images
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Western blot - Anti-ZSWIM2 antibody (ab127023)All lanes : Anti-ZSWIM2 antibody (ab127023) at 1/1000 dilution
Lane 1 : U87-MG whole cell lysate
Lane 2 : MCF7 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 73 kDa
7.5% SDS-PAGE
Protocols
References
ab127023 has not yet been referenced specifically in any publications.
