Overview

  • Product name

  • Description

    Rabbit polyclonal to ZSWIM2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 350-575 of Human ZSWIM2 (UniProt Q8NEG5).

  • Positive control

    • U87-MG and MCF7 whole cell lysates; NT2D1 and IMR32 cell lysates
  • General notes

    Store undiluted.

Properties

Applications

Our Abpromise guarantee covers the use of ab127023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 73 kDa.

Target

  • Function

    E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes.
  • Sequence similarities

    Contains 2 RING-type zinc fingers.
    Contains 1 SWIM-type zinc finger.
    Contains 1 ZZ-type zinc finger.
  • Domain

    The SWIM-type zinc finger is reqiered for ubiquitination activity.
  • Post-translational
    modifications

    Polyubiquitinated. Polyubiquitination is followed by degradation via the proteasome.
  • Information by UniProt
  • Database links

  • Alternative names

    • E3 ubiquitin-protein ligase ZSWIM2 antibody
    • MEKK1-related protein X antibody
    • MEX antibody
    • MGC33890 antibody
    • Zinc finger SWIM domain containing 2 antibody
    • Zinc finger SWIM domain containing protein 2 antibody
    • Zinc finger SWIM domain-containing protein 2 antibody
    • Zinc finger SWIM type containing 2 antibody
    • ZSWIM2 antibody
    • ZSWM2_HUMAN antibody
    • ZZ type zinc finger containing protein 2 antibody
    • ZZ-type zinc finger-containing protein 2 antibody
    • ZZZ2 antibody
    see all

Images

  • All lanes : Anti-ZSWIM2 antibody (ab127023) at 1/1000 dilution

    Lane 1 : U87-MG whole cell lysate
    Lane 2 : MCF7 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 73 kDa



    7.5% SDS-PAGE

References

ab127023 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127023.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up