Overview

  • Product name

  • Description

    Rabbit polyclonal to ZWINT
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Fusion protein corresponding to Human ZWINT aa 1-277. (BC020979).
    Sequence:

    MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKD KLLCSQLQVADFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELK ATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRR AVQNQWQLQQEKHLQHLAEVSAEVRERKTGTQQELDGVFQKLGNLKQQAE QERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQS TGDTMGRDPGVSFKAVGLQPAGDVNLP


    Database link: O95229

  • Positive control

    • Human thyroid cancer and colon cancer tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab197794 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.

Target

  • Function

    Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
  • Cellular localization

    Nucleus. Chromosome > centromere > kinetochore. Localizes to kinetochores from late prophase to anaphase.
  • Information by UniProt
  • Database links

  • Alternative names

    • Human ZW10 interacting protein 1 antibody
    • HZwint 1 antibody
    • HZwint1 antibody
    • KNTC 2 AP antibody
    • KNTC2AP antibody
    • MGC 117174 antibody
    • MGC117174 antibody
    • ZW10 interacting kinetochore protein antibody
    • ZW10 interacting protein 1 antibody
    • ZW10 interactor antibody
    • ZW10 interactor, kinetochore protein antibody
    • ZW10-interacting protein 1 antibody
    • ZWINT 1 antibody
    • ZWINT antibody
    • Zwint-1 antibody
    • ZWINT_HUMAN antibody
    • ZWINT1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling ZWINT with ab197794 at 1/50 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling ZWINT with ab197794 at 1/50 dilution.

References

This product has been referenced in:

  • Yuan W  et al. Bioinformatic analysis of prognostic value of ZW10 interacting protein in lung cancer. Onco Targets Ther 11:1683-1695 (2018). Read more (PubMed: 29615843) »
See 1 Publication for this product

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